Saturday, November 26, 2011
CarnoSyn® FAQs--Advanced (Product Development)
When we talk about new product development, often the questions revolve around the taste and stability of CarnoSyn®. This post is an attempt to cut straight to the point for every New Product Developer out there.
Does CarnoSyn® Beta-Alanine require a loading phase?
Yes. If you’re taking 3.2g per day, it typically takes from 4-6 weeks to reach maximum muscle carnosine levels. But the half life of Beta-Alanine in the body is approximately 49 days. So don't limit Beta-Alanine to pre-workouts. It can be added to various formulas to create "PERFORMANCE" proteins, BCAAs, EAAs, vitamins, water, energy drinks and more. Why not get more out your everyday products by adding CarnoSyn®?
Is Beta-Alanine hygroscopic?
Beta-Alanine is a white, free-flowing powder that is slightly hygroscopic. It generally poses no problem with moisture, but adding silica to a powder formula is often recommended to keep moisture low and flowability high.
What is the particle size?
Beta-Alanine is 20-40 mesh. The particle size variance between different manufacturers is extremely small. It is naturally granular. If you micronize it, it will take on more hygroscopic properties and you'll have to break up the clumps in production. Just FYI, micronizing Beta-Alanine is 100% marketing gimmick. It is worthless to micronize something so incredibly soluble and absorbable in water.
How does CarnoSyn® Beta-Alanine taste?
Beta-Alanine tastes neutral. It will not negatively impact a drink’s taste.
Is CarnoSyn® Beta-Alanine stable?
Yes, Beta-Alanine is stable in powder form. It is stable in heat (melting point is 210°C) and light, and it has a three-year shelf life in powder form in its original containers. Compound Solutions, Inc. is currently working on liquid stability. Two-month data suggests it is stable in water (RTDs).
Is CarnoSyn® Beta-Alanine soluble in water?
It is extremely soluble in water—55 grams per 100 milliliters of water.
Is CarnoSyn® Beta-Alanine easy to formulate with?
In terms of taste, solubility, stability and hygroscopicity, Beta-Alanine is one of the easiest ingredients in sports to formulate with.
What dosage forms can CarnoSyn® Beta-Alanine be used in?
Among others, powders, RTDs, gels, stick packs, confectionary, tablets and capsules.
Why not just take Carnosine?
Because ingesting Carnosine is costly and inefficient. Ingested Carnosine breaks into Beta-Alanine and Histidine and is then re-synthesized into Carnosine. It is estimated that the body uses only 60% of ingested Carnosine.
How much CarnoSyn® Beta-Alanine should be dosed in a product?
Most of the studies have used 3.2 grams per day. Because Beta-Alanine causes a tingling sensation called paresthesia, it is best to split the 3.2 gram dose into two to three doses per day. We have found 1.2 grams per dose is a good dose for the mass market because the tingling sensation is not overwhelming. However, many people in bodybuilding like to take up to 1.6 grams per dose for a more intense experience.
What is paresthesia?
It is a harmless tingling sensation many feel for 10 to 20 minutes after ingesting Beta-Alanine. Most people like the sensation because they can feel it working.
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